SOLUTIONS

TOYOPEARL MegaCap II-550 EC

TOYOPEARL MegaCap II SP-550EC

TOYOPEARL MegaCap II SP-550EC is a high capacity cation exchange resin optimized for the capture and purification of small proteins and peptides such as insulin. It is composed of polymethacrylate beads that have been functionalized with Sulfopropyl (SP) strong cation exchange groups.

TOYOPEARL MegaCap II SP-550EC is available 200 µm particle size (EC-grade) and can be used for high throughput capture and intermediate purification process steps. It exhibits typical dynamic binding capacities of 130 g/L for insulin and maintains this high capacity at increased linear velocities.

Structure of TOYOPEARL MegaCap II SP-550EC 

SP650_structure.jpg 

 

Product attributes

Pore size (mean): < 100 nm
Particle size (mean): 75 µm (C-grade)
Pressure rating: 0.3 Mpa
Shipping buffer: 20% ethanol
pH stability: 3-13
Shelf life: 10 years (estimated)

pKa values for Ion Exchange groups 

deae_fig1.png 

 

Ordering Information

P/N Description Dimension
0021804 TOYOPEARL MegaCap II SP-550EC 100 mL
0021805 TOYOPEARL MegaCap II SP-550EC 250 mL
0021806 TOYOPEARL MegaCap II SP-550EC 1 L
0021807 TOYOPEARL MegaCap II SP-550EC 5 L
0021870 ToyoScreen MegaCap II SP-550EC 6 x 1 mL
0021871 ToyoScreen MegaCap II SP-550EC 6 x 5 mL