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Lens3 MALS Detector

LenS3 Multi-Angle Light Scattering Detectors

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The next generation of LenS™3 MALS detector provides the latest in light scattering detection from Tosoh Bioscience. Technological advancements in instrument design and software simplify exact molecular weight (MW) and radius of gyration (Rg) determinations of polymers and biomolecules.

Building upon the powerful and unique optical design of the original LenS3 MALS detector, the new generation features a lower cell volume, thus preserving chromatographic resolution even with U/HPLC systems and columns. The higher dynamic range increases the scope of MW determination from low to high scattering samples, further simplifying the analysis of small polymers and high molecular weight viral vectors alike.
Along with its technical hardware improvements and its wide screen control panel, the new LenS3 MALS detector is powered by SECview™ 3.1 software. This innovation to the user interface allows higher productivity with semi-automation and a streamlined workflow when processing multiple data files. Furthermore, a proprietary algorithm based on the theory of light scattering removes the historical guesswork of selecting an appropriate model for MALS calculations.

We’ve worked tirelessly in our labs developing our MALS solution to make sure your experience is hassle-free.
Introducing the new generation of LenS3 MALS detector and SECview software: light scattering made easy, for all.

Based on the first generation of LenS3 MALS detector and equipped with an integrated viscometer, the LenS3 MALS-V dual detector offers a simple and compact solution for triple detection measurements when combined with a concentration detector (RI or UV). Just like with light scattering data, the SECview software includes seamless viscometry data acquisition and processing to get the most out of advanced detection GPC/SEC analyses.

The intrinsic viscosity (IV) of polymers reflects how dense and how flexible polymer chains are in dilute solutions. The lower the IV, the more compact the polymer is while rigid polymer chains show a higher IV than flexible random coils. When combined with light scattering measurements, the MW and IV distributions provide a wealth of structural information about polymers.”