What’s in our names - Process Resins

Tosoh Bioscience has the most comprehensive selection of process media resins, with a variety of pore and particle size combinations for several modes of chromatography. When it comes to naming our resins, we’ve got it down to a science (literally). Here’s how you can identify the right resin for your purification process:

1. Resin Type

Tosoh Bioscience offers two base beads for our resin products: TOYOPEARL® and TSKgel®. TOYOPEARL and TSKgel products are hydroxylated methacrylic polymer resins and are offered in many different pore sizes and particle diameters. The key differences between the two types are particle size availability, degree of crosslinking, dynamic binding capacity, and operating pressures. Since similarly functionalized TOYOPEARL and TSKgel resins have the same backbone polymer chemistry, the selectivity remains the same as you scale up or down.

2. Ligand

TOYOPEARL or TSKgel resins are available in the following modes of chromatography functionalized with these ligands:

3. Pore Size

TOYOPEARL or TSKgel resins are available in the following pore sizes:

4. Particle Size

Particle size is typically denoted in the product name as letters or numbers denoting the grade.

5. Additional Abbreviations

Some of our products have additional features or need clarification about what type of product they are.

What does “HW” stand for when talking about Toyopearl HW size exclusion resin?

Literally, the HW stands for Hydrophilic Water-compatible; referring to the nature of the polymeric bead used for the size exclusion resin. The size exclusion bead is also the backbone for all of the other Toyopearl resins.