TOYOPEARL SuperButyl-550C
TOYOPEARL SuperButyl-550C is based on a 50 nm (500 Å) pore size polymethacrylate base material bonded with C4 groups. It has the second highest hydrophobicity of the TOYOPEARL HIC resins. Its pore size is the smallest of our three butyl resins.
Primary applications are for the separation of smaller proteins. Depending on the feedstock's molecular size profile, it is also useful in negative or flow through chromatography. It can be used for capture and intermediate purification process steps.
Structure of TOYOPEARL SuperButyl-550C
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Product attributes
| Pore size (mean): |
50 nm |
| Particle size (mean): |
100 µm (C-grade) |
| Shipping buffer: |
20% ethanol |
| pH stability: |
>1-13 |
| Stability data: |
10 years (estimated) |
Typical dynamic binding capacities for humanized mAb
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Binding capacitiy (mg/mL - gel)
(10% breakthrough)
Phenyl-650M 35.2
Butyl-650M 42.1
PPG-600M 44.8
Butyl-600M 48.5 |
Selectivity of TOYOPEARL HIC resins
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| Samples: 1. Ribonuclease A, 2. Lysozyme, 3. α- Chymotrypsinogen |