Tosoh Bioscience introduces new hydroxyapatite medium specifically designed for the purification of monoclonal and polyclonal antibodies, including IgG, IgA, IgM, antibody fragments, fusion- and phosphoproteins, and the separation of single-stranded and double-stranded DNA.
Tosoh Bioscience sets a new standard for hydroxyapatite with Ca++Pure-HA
Tosoh Bioscience introduces a new hydroxyapatite medium. Ca⁺⁺Pure-HA provides exceptional separation properties and unequaled selectivity and resolution for the purification of multiple classes of biomolecules. Ca++Pure-HA supports the continuous effort of the pharmaceutical industry to reduce the manufacturing costs of biological drugs.
Ca⁺⁺Pure-HA is a hydroxyapatite resin used in the chromatographic separation of biomolecules. Key applications for the use of Ca⁺⁺Pure-HA include the purification of monoclonal and polyclonal antibodies, including IgG, IgA, IgM, antibody fragments, fusion- and phosphoproteins, and the separation of single-stranded and double-stranded DNA.
Ca⁺⁺Pure-HA has a demonstrated dynamic binding capacity (DBC), at 5% breakthrough, of 55 mg mAb/mg at 5 minute residence time. Ca⁺⁺Pure-HA has been sintered at high temperatures for increased mechanical and pH stability, allowing it to withstand the rigors of industrial-scale applications. The robust nature of Ca⁺⁺Pure-HA offers the flexibility to use this medium at any stage in a process from capture to final polishing.
Tosoh Bioscience’s Ca++Pure-HA is available for orders as of today. Contact your local sales representative to receive more information.
